2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1453R
    Hypocrellin B (Standard)
    		Inhibitor
    Hypocrellin B (Standard) is the analytical standard of Hypocrellin B. This product is intended for research and analytical applications. Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3].
    Hypocrellin B (Standard)
  • HY-126744
    Juncin E
    		Inhibitor
    Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm.
    Juncin E
  • HY-B1703R
    Nifursol (Standard)
    		Inhibitor
    Nifursol (Standard) is the analytical standard of Nifursol (HY-B1703). This product is used for research and analytical applications. Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals.
    Nifursol (Standard)
  • HY-118495
    Cardol diene
    		Inhibitor
    Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability.
    Cardol diene
  • HY-126571
    Virustomycin A
    		Inhibitor
    Virustomycin A is a nature product that could be isolated from Streptomyces. Virustomycin A has selective and potent antitrypanosomal activity.
    Virustomycin A
  • HY-B1401
    Euquinine
    		Inhibitor
    Euquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .
    Euquinine
  • HY-W010668R
    Quinine sulfate hydrate (Standard)
    		Inhibitor
    Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
    Quinine sulfate hydrate (Standard)
  • HY-106866
    Bulaquine
    		Inhibitor
    Bulaquine (CDRI 80/53) is a potent antimalarial agent which is an analogue of Primaquine (HY-12651A). Bulaquine affects multiple metabolism pathways and shows inhibition effect on Plasmodium cynomolgi infection. Bulaquine can be used for the research of malaria.
    Bulaquine
  • HY-183262
    Antileishmanial agent-40
    		Inhibitor
    Antileishmanial agent-40 is an orally active and selective antileishmanial agent. Antileishmanial agent-40 elevates intracellular reactive oxygen species (ROS) levels in Leishmania donovani promastigotes. Antileishmanial agent-40 induces cell cycle arrest at the sub-G0/G1 phase in Leishmania donovani promastigotes, indicative of programmed-like parasite death. Antileishmanial agent-40 can be used for the research of leishmaniasis.
    Antileishmanial agent-40
  • HY-12987S2
    Pimozide-d4-1
    		Inhibitor
    Pimozide-d4-1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
    Pimozide-d<sub>4</sub>-1
  • HY-128399
    CpCDPK1/TgCDPK1-IN-3
    		Inhibitor
    CpCDPK1/TgCDPK1-IN-3 (Compound 20) is a CpCDPK1 and TgCDPK1 inhibitor with IC50 values of 0.003 and 0.0036 µM, respectively. CpCDPK1/TgCDPK1-IN-3 can be used in the research of apicomplexan protozoa-related diseases, such as the research of T. gondii, C. parvum and C. hominus infection.
    CpCDPK1/TgCDPK1-IN-3
  • HY-155400
    Antitrypanosomal agent 17
    		Inhibitor
    Antitrypanosomal agent 17 (Compd 7a) possesses antiamastigote activity, with an IC50 of 0.03 μM against T. congolense strain IL3000.
    Antitrypanosomal agent 17
  • HY-115905
    Antimalarial agent 9
    		Inhibitor
    Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity.
    Antimalarial agent 9
  • HY-150066
    Antimalarial agent 16
    		Inhibitor
    Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can inhibit P. falciparum parasite growth (IC50=2.0 nM).
    Antimalarial agent 16
  • HY-17530S
    Aldicarb sulfone-13C2,d3
    		Inhibitor
    Aldicarb sulfone-13C2,d3 is the deuterium and 13C labeled Aldicarb sulfone (HY-17530). Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase.
    Aldicarb sulfone-<sup>13</sup>C<sub>2</sub>,d<sub>3</sub>
  • HY-115721
    Antimalarial agent 2
    		Inhibitor
    Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.
    Antimalarial agent 2
  • HY-129716
    L-693989
    		Inhibitor
    L-693989 is an orally active water-soluble lipopeptide with anticandidal and antipneumocystis activity. L-693989 is effective in preventing the development of both P. carinii cysts. L-693989 is promising for research of P. carinii pneumonia.
    L-693989
  • HY-157314
    HDAC6-IN-27
    		Inhibitor
    HDAC6-IN-27 (compound 8C) is a HDAC inhibitor with IC50 vales of 15.9 nM 136.5 nM and 6180.2 nM for HDAC6, HDAC8 and HDAC1, respectively. HDAC6-IN-27 shows potent antiparasitic effects.
    HDAC6-IN-27
  • HY-114489B
    Haemanthamine hydrochloride
    		Inhibitor
    Haemanthamine hydrochloride is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine hydrochloride targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine hydrochloride has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities.
    Haemanthamine hydrochloride
  • HY-160681
    OvCHT1-IN-1
    		Inhibitor
    OvCHT1-IN-1 (compound 3i) is a potent OvCHT1 inhibitor with IC50 of 0.6 μM .
    OvCHT1-IN-1
Parasite Isoform Comparison

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